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ASCP ASCP-MLT Exam Syllabus Topics:
| Section | Objectives |
|---|---|
| Topic 1: Microbiology | - Clinical microbiological techniques
|
| Topic 2: Clinical Chemistry | - Metabolic and analytical testing
|
| Topic 3: Laboratory Operations | - Quality and safety in the clinical lab
|
| Topic 4: Urinalysis and Body Fluids | - Fluid analysis and interpretation
|
| Topic 5: Blood Banking / Immunohematology | - Blood group systems and antibody identification
|
| Topic 6: Hematology | - Blood cell analysis and disorders
|
ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:
1. A young man is experiencing difficult breathing after fainting. The physician orders a blood gas analysis which shows the following results:
pH = 7.25
pCO2 = 62 mmHg
pO2 = 70 mmHg
HCO3 = 23 mEq/L
Which condition is most likely afflicting this patient?
A) metabolic alkalosis
B) respiratory acidosis
C) respiratory alkalosis
D) metabolic acidosis
2. Provide the equivalent measurement for one pint.
A) 0.474 liters
B) 4.2 liters
C) 0.25 liters
D) 0.1 liter
3. G6PD deficiency causes an increased suseptibility to the oxidation of hemoglobin, which in turn, causes the precipitation of hemoglobin inside of the red blood cell.
Which one of the following conditions is associated with glucose-6-phosphate dehydrogenase (G6PD) deficiency?
A) Hemoglobins with low oxygen affinities
B) Precipitation of hemoglobin
C) Faulty heme synthesis
D) Microcytic red cells
4. Type I hyperlipoproteinemia is a form of hyperlipoproteinemia associated with deficiencies of lipoprotein lipase. Hyperlipoproteinemia type II is the most common form and is classified into type IIa and type IIb, depending on whether there is elevation in the triglyceride level in addition to LDL cholesterol.
Hyperlipoproteinemia type III is associated with high chylomicrons and IDL. Hyperlipoproteinemia type IV is assoicated with high triglycerides. It is also known as hypertriglyceridemia. Hyperlipoproteinemia type V is similar to type I, but with high VLDL in addition to chylomicrons.
An obese adult with premature arteriosclerosis is seen in the clinic. When her serum is tested no chylomicrons are present, LDL are normal and VLDL are increased. There is an increase in triglycerides and slight increase in cholesterol. Lipoprotein electrophoresis reveals a heavy pre-beta band. She has no skin rash and uric acid is increased. This patient has a hyperlipoproteinemia with the MOST likely type of:
A) V
B) III
C) VI
D) IV
E) II
5. HLA-DR is a class II MHC.
HLA-A, HLA-B, and HLA-C are all class I MHC.
Which of the following antigens is classified as a Major Histocompatibility Complex Class II antigen (MHCII)?
A) HLA-DR
B) HLA-A
C) HLA-C
D) HLA-B
Solutions:
| Question # 1 Answer: B | Question # 2 Answer: A | Question # 3 Answer: B | Question # 4 Answer: D | Question # 5 Answer: A |



